David Watt

David is the Technical Director in the Business Development Department at WellSpring, and has over twenty years of pharmaceutical GMP experience in technical definition and evaluation of Contract Development and Manufacturing projects, both from provider and client perspectives. David has previously worked at Valeant, Medicis, Patheon and Syntex Pharmaceuticals. David is responsible for overseeing all technology transfer activities in the organization.
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Recent Posts

What Are Feasibility Studies And How Are They Used In The Pharmaceutical Industry?

Posted by David Watt

A feasibility study is probably the single most important consideration in the development of a drug. It’s where we begin to elucidate the formula, the process, the equipment train - where we identify the upfront variables that must be reckoned with. When developing a new process, whether it concerns a new product or an existing product, issues with quality or an inefficient process, it's always necessary and beneficial to develop a feasibility plan.

A good feasibility plan should clearly state the objectives of the project and will entail a series of experiments to determine what preexisting issues may exist. In the absence of potential issues, it should identify the critical processing factors that coalesce to consistently manufacture and reproduce a quality product.

Factors To Consider When Developing A Feasibility Plan

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Topics: Manufacturing Scale-Up

What’s the Best Way to Scale Up High Shear and Fluid Bed Processes?

Posted by David Watt

A common question for pharmaceutical companies using high shear granulation and fluid bed drying processes for producing their product is – what’s the best way to scale the production up?

The first step that we use with many of our clients is to perform stability and full scale development batches to determine the critical process parameters and attributes. The immediate goal is to develop a manufacturing process that will produce a safe, quality product which meets the attributes and specifications based on a detailed technical transfer document from the donor company.

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Topics: Manufacturing Scale-Up